Valera Nattokinase

Talk to your doctor first. We mean that literally — don't start this without asking.

Nattokinase supports the body's normal fibrinolytic activity, and taking it alongside warfarin, Eliquis, Xarelto, Plavix, or daily aspirin may increase bleeding risk. The same goes if you have a bleeding or clotting disorder, or a history of DVT. If you have surgery or a dental procedure scheduled, stop taking it two weeks beforehand and tell your surgeon.

We'd rather lose the sale than have you find this out the hard way.

FU stands for fibrinolytic units — a measure of the enzyme's activity, not its weight in milligrams. Two products can both say "nattokinase" and differ enormously in how much active enzyme is actually in there.

It matters because the research is dose-dependent. In the 2022 twelve-month study of 1,062 adults, the group taking roughly 10,800 FU per day showed measurable changes on the markers researchers tracked. The group at 3,600 FU showed none. Same ingredient, different dose, different result.

That's the entire reason our serving size is 10,800 FU.

We don't know, and anyone who gives you a specific timeline is guessing.

The research that looked at measurable changes ran over months, not days — twelve months in the largest study, twenty-six weeks in another. Nattokinase isn't a stimulant; there's no same-day effect to feel. Some people report noticing something in their daily routine within a couple of months.

That's exactly why our guarantee runs 90 days instead of two weeks — you need real time to judge it.

Nattokinase has been consumed in Japan for centuries as natto, and the studies we cite ran twelve months without safety concerns reported in the treatment groups.

That said, if you're on medication — especially blood thinners or blood pressure medication — or you have a medical condition, run it by your doctor before starting and let them know it's part of your routine. Same goes if anything changes.

Nattokinase is produced by fermenting soybeans with Bacillus subtilis. The extraction and purification process removes most soy protein, and many soy-sensitive people tolerate it, but "most" isn't "all" and residual soy protein can remain.

If your soy allergy is severe, this isn't a risk worth taking on our say-so. Check with your doctor or allergist before taking it.

"Enteric" just means intestine. An enteric coating is a protective layer that stays intact in the acidic environment of your stomach and only dissolves once it reaches the more neutral pH of the small intestine.

That matters because nattokinase is an enzyme, and without protection, a meaningful share of the dose can be broken down before it ever gets absorbed — which is one reason a product can list a big FU number on the label and still deliver very little. The coating is what makes the dose on the front of the bag mean something.

As for what's in it: MCT oil (from coconut oil), softgel (gelatin, glycerin, purified water), and yellow beeswax. It contains Soy & Tree Nuts (coconut). Valera does NOT contain wheat, dairy, or gluten.

If you choose Subscribe & Save, we send you a fresh bottle on your chosen interval (every 30, 90, or 150 days) and you save 20% on every shipment.

You can pause, skip, change frequency, or cancel any time from your account dashboard — no calls, no emails, no questions asked.

Eligible purchases are covered by our 90-Day Satisfaction Guarantee. We ask that you use the product for at least 80 days after delivery and submit your request no later than Day 90. No physical return is required. See our Returns & Refunds Policy for full terms.

A lot of companies give you two weeks or 30 days and hope you don't notice whether it worked. We think that's backwards. If we believe in what we're selling, we give you enough time to actually find out.